Download Image-Guided Stereotactic Radiosurgery: High-Precision, by Harun Badakhshi PDF

By Harun Badakhshi

This booklet presents the reader with a close replace at the use of stereotactic radiosurgery (SRS) in sufferers with lesions of the mind and different components of the physique. the purpose isn't just to clarify the applying of SRS and rfile its price with regards to the author's personal scientific studies and different released proof, but additionally to contextualize the know-how inside a brand new strategic inspiration of melanoma care. while embedded inside a suitable conceptual framework, know-how turns into pivotal in altering healing concepts. a brand new paradigm that's more and more impacting on scientific perform is the oligometastatic kingdom, at the foundation that long term survival will be completed in sufferers with a low quantity and variety of metastatic lesions. This publication hence addresses the price of SRS in sufferers with oligometastases of good tumors to the mind, lung, backbone, and liver. furthermore, it examines using SRS in sufferers with different mind lesions, early-stage degree lung melanoma, liver melanoma, and early-stage prostate melanoma. Readers might be persuaded that SRS, utilizing state of the art imaging applied sciences to bring accurately distinctive radiation remedy, represents a thrilling non-invasive strategy that holds nice promise for the current and the way forward for melanoma care.

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Extra info for Image-Guided Stereotactic Radiosurgery: High-Precision, Non-invasive Treatment of Solid Tumors

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Dewhirst MW, Cao Y, Moeller B, Li CY. The cycle between angiogenesis, perfusion, and hypoxia in tumors. In: Teicher BA, editor. Cancer drug resistance. Totowa: Humana Press; 1996. p. 3–24. 32. Folkman J. Tumor angiogenesis. Adv Cancer Res. 1985;43:175–203. 33. Yancopoulos GD, Klagsbrun M, Folkman J. Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border. Cell. 1998;93:661–4. 34. Konerding MA, Ackern CV, Fait E, et al. Morphological aspects of tumor angiogenesis and microcirculation.

Basic research on the molecular effects of fractionated radiotherapy has yielded a wide range of clinical research, including clinical trials, in the last three decades. The experts in this field undertook huge efforts with regard to laboratory experimentation and clinical studies to understand the real meaning of fractionation and its effects in clinical practice. These processes are ongoing and characterized by significant scientific intensity. On the other hand, experimental research has been rudimentary, with a focus on the radiation effects of single-dose high-precision radiotherapy; in other words, all work has attempted to reveal the biologic essence of so-called radiosurgery.

7. Bachelard G. Le nouvel esprit scientifique. The new scientific spirit (trans: Goldhammer A). Boston: Beacon Press; 1985. 8. Halsted WS. Operative treatment of cancer of the breast. Maryland Med J. 1894;1:109. 9. Halsted WS. The results of operations for the care of cancer of the breast performed at the Johns Hopkins hospital from June, 1889, to January, 1894. Ann Surg. 1894;20(5):497–555. 10. Halsted WS. A clinical and histological study of certain adenocarcinomata of the breast: and a brief consideration of the supraclavicular operation and of the results of operations for cancer of the breast from 1889 to 1898 at the Johns Hopkins Hospital.

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